Product Name:MM 54
Synonyms:受体拮抗剂多肽MM 54
CAS No.:1313027-43-8
Catalog No.:GT-P2789
Description:MM 54 是一种有效的 apelin 受体拮抗剂多肽(Ki = 82 nM;IC50 = 93 nM),是由14个氨基酸组成的环状多肽,能起到拮抗 [Pyr1]-Apelin-13 对毛喉素诱导的 CHO-K1-APJ 细胞中 cAMP 积累的抑制作用, 在胶质母细胞瘤小鼠异种移植模型中减少肿瘤扩张并延长存活时间。
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Vacuum-packed with aluminum foil bag or transparent bag. 10mg,50mg,100mg,1g,10g, 50g per package with icebag. Or according to your request.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(3-letter code) |
CRPRLCKHCRPRLC(Disulfide bridge:Cys1-Cys6;Cys9-Cys14) |
Sequence(1-letter code) |
H-Cys-Arg-Pro-Arg-Leu-Cys-Lys-His-Cys-Arg-Pro-Arg-Leu-Cys-OH(Disulfide bridge:Cys1-Cys6;Cys9-Cys14) |
Peptide Structure |
|
Molecular Formula |
C70H121N29O15S4 |
Molecular Weight |
1737.16 |
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